Description
The HM track is the histone modification regions inferred from ChIP-seq experiment. Data were collected from GEO datasets.
Method
Reads were mapped to unmasked genomes using bowtie2 (v2.2.8) and at most 1 mismatch in seed alignment was allowed (-N 1). Macs2 (v2.1.1.20160309) was used for peak calling. For histone modification, this process was performed with options of "--broad".
Reference
Langmead, B., & Salzberg, S. L. (2012). Fast gapped-read alignment with Bowtie 2. Nat Methods, 9(4), 357-359. doi:10.1038/nmeth.1923
Feng, J., Liu, T., Qin, B., Zhang, Y., & Liu, X. S. (2012). Identifying ChIP-seq enrichment using MACS. Nat Protoc, 7(9), 1728-1740. doi:10.1038/nprot.2012.101
Data Source
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