Description
This track shows an example of motif frequencies of a transcription factor (TF) binding motif in corresponding genomic positions.
Methods
Given a TF binding site and corresponding binding motif, the motif frequency of each base pair was extracted according to genomic sequence.
Here is the TF binding motif matrix:
A C G T
0.209830 0.073724 0.410208 0.306238
0.659735 0.274102 0.024575 0.041588
0.039698 0.831758 0.034026 0.094518
1.000000 0.000000 0.000000 0.000000
0.013233 0.954631 0.032136 0.000000
0.022684 0.017013 0.943289 0.017013
0.000000 0.052930 0.000000 0.947070
0.000000 0.000000 1.000000 0.000000
0.009452 0.017013 0.283554 0.689981
0.083176 0.882798 0.000000 0.034026
0.527410 0.107750 0.293006 0.071834
The corresponding genomic sequence (Chr1:8219814-8219824 +) is:
TACACGTGTCT
So the corresponding motif frequency of each base pair was highlighted below:
A C G T
0.209830 0.073724 0.410208 0.306238
0.659735 0.274102 0.024575 0.041588
0.039698 0.831758 0.034026 0.094518
1.000000 0.000000 0.000000 0.000000
0.013233 0.954631 0.032136 0.000000
0.022684 0.017013 0.943289 0.017013
0.000000 0.052930 0.000000 0.947070
0.000000 0.000000 1.000000 0.000000
0.009452 0.017013 0.283554 0.689981
0.083176 0.882798 0.000000 0.034026
0.527410 0.107750 0.293006 0.071834
The extracted motif frequencies were:
0.306238, 0.659735, 0.831758, 1.000000, 0.954631, 0.943289, 0.947070, 1.000000, 0.689981, 0.882798, 0.071834
References
Jin, J., Tian, F., Yang, D. C., Meng, Y. Q., Kong, L., Luo, J., & Gao, G. (2017). PlantTFDB 4.0: toward a central hub for transcription factors and regulatory interactions in plants. Nucleic Acids Res, 45(D1), D1040-D1045.
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